Superficially, the men's sperm seemed healthy, with the quantity, shape and ability to move all showing as normal.
But closer inspection revealed that the proportion with DNA damage rose from 13.8 per cent to 30.3 per cent after just four weeks, New Scientist magazine reports.
And, of course, the drug has had other problems:
Seroxat was hailed as a wonder drug when it was first sold in Britain in 1990.
But it was later linked to child suicides, mood swings, nightmares and personality changes.
It was banned for under-18s in 2003 but is still prescribed for adults.
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